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As of August 9, 2026, NATERA INC (Common Stock), ticker 45E (NTRA) trades at $322.10. CleaRank Financial AI rates it Sell with a fair value of $250.00, 22.4% below the current price. RSI at 76 is in overbought territory, and the price is above its 50-day average of $252.56.

NATERA INC (Common Stock) – ticker 45E (NTRA)

NATERA INC (Common Stock) – ticker 45E NASDAQ

$322.10 56.72 (21.37%)
At close: Aug 7, 4:00 PM EDT
AI Analyst Consensus
Sell
25 / 100

Natera Inc. (NTRA) is currently trading at $322.10, a level that appears stretched given its negative EPS of -1.62. The company has demonstrated impressive revenue growth of 38.8%, but this is overshadowed by significant insider selling totaling $383.8 million against zero purchases, leading to a heavy insider selling verdict. Technically, the stock is exhibiting extreme overbought conditions with an RSI of 76.14 and a Stochastic reading of 98.79, suggesting a high probability of a pullback.

While the strong revenue growth is a positive fundamental indicator for Natera Inc. in the Diagnostics & Research industry, the confluence of negative profitability, aggressive insider divestitures, and overextended technicals presents a compelling risk-reward scenario favoring caution. Investors should monitor for any signs of trend reversal or a shift in insider sentiment.

NTRA Price Analysis

Market Metrics

Open
$320.90
Day Range
$306.38 to $323.01
Prev Close
$265.38
Volume
3.39M
52-Week Range
$131.81 to $323.01
Market Cap
$46.13B

Peer Benchmarking

Valuation vs Sector (Healthcare)

Performance vs XLV

Sector Position Analysis
The stock's valuation metrics position it within the sector's competitive landscape, reflecting its market standing and growth trajectory relative to industry peers.

NTRA Analysis

Company's Health 2/5
AI Analyst Target -8.00% Downside
Target Price
$296.33
AI Technical Analysis Sell

Natera Inc. (NTRA) is exhibiting highly overbought technical conditions. The Relative Strength Index (RSI) stands at 76.14, well above the 70 threshold, indicating the stock is in overbought territory and susceptible to a correction. Similarly, the Stochastic Oscillator at 98.79 reinforces this sentiment, suggesting extreme upward momentum that is unsustainable in the short term. The MACD at 8.20 also indicates strong bullish momentum, but in conjunction with the RSI and Stochastic, points to a potential reversal.

The stock is trading significantly above its key moving averages: the 50-day SMA ($252.56), the 200-day SMA ($223.09), and the 20-day EMA ($270.90). While this demonstrates a strong uptrend, the magnitude of the deviation, particularly from the 20-day EMA, suggests it is extended. The Commodity Channel Index (CCI) at 377.74 further confirms the extreme bullishness and potential for a reversion to the mean. Key support levels will be critical to watch should a pullback materialize.

ProTips
  • Monitor insider transaction filings closely for any change in selling pressure or initiation of buying activity, as this has been a strong signal for NTRA.
  • Given the extreme overbought RSI (76.14) and Stochastic (98.79), consider implementing tighter stop-loss orders or reducing position size to mitigate risk from a potential pullback.
  • The company's negative EPS and substantial market cap highlight the importance of tracking its progress towards profitability and managing cash burn effectively.
Key Catalysts
Bearish Heavy Insider Selling Pressure

Insiders have sold $383.8 million in stock with no reported purchases, signaling a potential lack of confidence in future price appreciation and contributing to a heavy insider selling verdict.

Source: Insider Filings
Bearish Extreme Overbought Technical Conditions

RSI at 76.14 and Stochastic at 98.79 indicate the stock is significantly overextended, increasing the likelihood of a short-term price correction.

Source: Technical Analysis
Neutral Strong Revenue Growth Trajectory

Natera Inc. continues to demonstrate robust top-line growth of 38.8%, indicating strong market demand for its diagnostic and research services.

Source: Company Financials
Bearish Persistent Negative Profitability

The company's negative EPS of -1.62 highlights ongoing profitability challenges, raising concerns about the sustainability of its high market capitalization.

Source: Company Financials
Market Outlook

The outlook for Natera Inc. (NTRA) in the next 6-12 months is cautious, leaning bearish in the short term. The current technical setup is highly overextended, suggesting a correction is probable. The significant insider selling further reinforces this view, indicating that those closest to the company may see limited near-term upside or increased downside risk. While the 38.8% revenue growth is a strong positive, it is currently insufficient to offset the concerns around profitability and insider sentiment.

A potential downside target could be the 50-day SMA at $252.56 or even the 200-day SMA at $223.09 if the selling pressure intensifies. Upside potential would require a significant shift in insider behavior, a clear path to profitability, or a cooling of technical overbought conditions. Without these catalysts, the stock faces headwinds that could lead to a re-evaluation of its current market valuation.

Key Statistics

Market Cap 46.13B
P/E Ratio N/A (Negative EPS)
EPS (TTM) -1.62
Dividend Yield 0.00%
52 Week High 323.01
52 Week Low 131.81

Natera Inc. (NTRA) presents a challenging fundamental picture, primarily due to its negative Earnings Per Share (EPS) of -1.62, rendering its Price-to-Earnings (P/E) ratio mathematically negative and indicating a lack of profitability. Despite a robust revenue growth rate of 38.8%, the company is not yet translating this top-line expansion into bottom-line profits. This divergence suggests potential issues with cost management or pricing power within its Diagnostics & Research industry segment.

The market capitalization of over $46 billion for a loss-making entity warrants scrutiny. While strong revenue growth is a positive indicator for future potential, the current valuation appears disconnected from profitability metrics. Investors should closely examine the company's path to profitability and its ability to sustain such high growth rates to justify its current market valuation. Competitors like ILMN and DGX operate in similar spaces, and their valuation multiples may offer a comparative benchmark, though NTRA's growth rate is notably higher.

Earnings & Growth Analysis

Natera Inc. (NTRA) is currently operating with a negative EPS of -1.62, indicating a loss-making position. While specific recent earnings beats or misses are not detailed in the provided data, the persistent negative EPS suggests that the company is prioritizing growth and market expansion over immediate profitability. The strong revenue growth of 38.8% indicates healthy demand for its diagnostic and research services.

The focus for Natera Inc. will be on its ability to scale its operations efficiently to eventually achieve profitability. Investors will be looking for a clear trajectory towards positive EPS and net margins. Without this, the current high valuation, supported only by revenue growth, carries significant risk, especially if growth rates decelerate or market conditions tighten.

Key Risks

The primary risk for Natera Inc. (NTRA) is its extreme overbought technical condition, with an RSI of 76.14 and a Stochastic of 98.79, signaling a high probability of a short-term price correction. Compounding this is the significant insider selling, with $383.8 million in sales and no reported purchases, indicating a lack of confidence from management and a heavy insider selling. Furthermore, the company's negative EPS of -1.62 highlights ongoing profitability challenges despite strong revenue growth, making its current market capitalization of over $46 billion appear stretched.

Technical Indicators i

RSI (14) 76.14
MACD 8.20
SMA 50 252.56
SMA 200 223.09
Technical Rating Bullish
RSI
Overbought
SMA Cross
Bullish
Price vs SMA
Bullish
MACD
Bullish
Golden Cross in effect with the 50-day SMA ($252.56) above the 200-day SMA ($223.09), price action is firmly bullish above key moving averages, RSI at 76.1 indicates overbought conditions; consider caution for immediate entries.

Market Correlations

How this stock moves relative to other assets

Based on 1 year of daily price data. Correlations may vary over different time periods.

S&P 500 (SPY) +0.45
Moderate correlation
Nasdaq 100 (QQQ) +0.44
Moderate correlation
Bitcoin (BTC) -0.02
Weak correlation
Gold (XAU) +0.11
Weak correlation
Check Custom Correlation

NTRA Trade Plans

Specific entry, exit, and risk management levels

Select Your Trade Bias
Risk Tolerance
Conservative 2% Aggressive
Portfolio Value
$
Position Size: Enter portfolio size →

🔴 SHORT ENTRY (click to switch)

CONSERVATIVE
$328.54
2% above current price
Lower risk, wait for rally
AGGRESSIVE
$322.10
Short at current price
Higher risk, chasing the move

Risk Management

STOP LOSS
$360.64
MAX LOSS
-9.8%
Volatility-Adjusted Stop Loss
Calculated based on RSI (76.1) and current market volatility

Profit Targets (Based on Conservative Entry)

TARGET 1
$312.11
-5% (Conservative)
-3.1% (Aggressive)
TARGET 2
$295.69
-10% (Conservative)
-8.2% (Aggressive)
TARGET 3
$279.26
-15% (Conservative)
-13.3% (Aggressive)
Consider scaling out: Take 50% profit at Target 1, 30% at Target 2, let 20% run to Target 3
⚠️ High-Volatility Risk Disclaimer
NTRA is classified as a high-volatility asset (Daily Vol: 4.48%). Aggressive price swings can lead to rapid capital loss. Liquidity risks may prevent exiting trades at desired prices. This AI-generated analysis is for educational purposes only and is not financial advice. Generated on August 9, 2026.

Compare Stocks

Compare stocks against top peers and benchmarks.

NTRA
322.10
21.37%
+ Compare

Risk & Volatility i

Risk Level Very High
Daily Volatility
4.48%
30-day average
52-Week Range
$131.81 144% from low $323.01
Risk Considerations
Monitor position sizing based on current volatility levels
Consider stop-loss placement beyond recent price range
Diversification helps mitigate single-stock risk exposure

Growth of $10,000

Compare with Another Ticker

Monte Carlo Projection (10yr)

NTRA Insider Trading Analysis

Source: SEC Form 4
Bought
None
No open-market buys
Sold
$383.8M
190 Transactions
Insiders
18
Active Traders
$
Avg Transaction
$2.0M
Large trades
Date Insider Type Shares Value

Frequently Asked Questions

Natera Inc.'s Relative Strength Index (RSI) is at 76.14 and its Stochastic Oscillator is at 98.79, both indicating that the stock has experienced a rapid price increase and is considered overbought. This suggests a potential for a price pullback as traders may look to take profits.
Insiders have sold $383.8 million worth of Natera Inc. stock with no reported purchases, resulting in a heavy insider selling. This indicates a lack of confidence from management and a potential bearish sentiment regarding the stock's near-term prospects.
Natera Inc. has a negative EPS of -1.62, meaning it is currently unprofitable. This makes traditional P/E ratio of -198.83 (negative due to EPS of $-1.62) billion is not supported by current earnings, relying heavily on future growth expectations.
The AI rating is 'Sell' due to the combination of extreme overbought technicals (RSI 76.14), significant insider selling ($383.8M net sales), and negative profitability (EPS -1.62). These factors outweigh the positive 38.8% revenue growth, suggesting a high risk of a price correction.
Key support levels to watch for Natera Inc. would include its 50-day Simple Moving Average (SMA) at $252.56 and its 200-day SMA at $223.09. A break below these levels could signal a more significant trend change.
Natera Inc.'s revenue growth of 38.8% significantly outpaces the sector average of 10.0% for Healthcare. However, this strong top-line performance is not yet translating into profitability, as indicated by its negative EPS.
The primary near-term risk for Natera Inc. is a potential price correction driven by its extreme overbought technical indicators and substantial insider selling, which could trigger profit-taking and a reversal of the recent upward trend.