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Stock·NASDAQ·Healthcare

Replimune Group, Inc. (REPL)

$10.86 -0.8900 (-7.57%)
At close: Oct 16, 4:00 PM EDT
Hold
49 / 100
CleaRank AI scorei
Market cap
$1.02B
Dividend yield
0.00%
Street target
$19.50median of 8 analysts
52-week range
$1.50 $16.33
01

The short version

Where REPL stands today, in four lines, and what CleaRank Financial AI makes of it.

REPL at a glance

Replimune Group, Inc. (REPL): Hold, 49/100 on CleaRank's AI score.

  • Trend Mixed: the price is above its 200-day but below its 50-day moving average ($9.05 and $13.77).
  • Earnings REPL beat estimates in 1 of its last 6 quarters, yet fell the next day after every one of them.
  • Insiders Insiders sold $2.6M and made no open-market purchases over the last 18 months.

Figures as of October 17, 2026.

CleaRank Financial AI

Replimune Group, Inc. (REPL) earns a CleaRank rating of Hold and a model score of 49/100.

Analysts lift the score the most, with 7 of 8 rating the stock a buy and a median target 79.6% above the price. Momentum drags hardest: the 14-day RSI of 31.9 is in the bearish zone and the MACD line is negative. The trend is mixed, with the price 21.15% below its 50-day average of $13.77 yet 20.06% above its 200-day average of $9.05. Across the past year, the stock gained 132.55%.

Only on CleaRank

Figures we compute ourselves from REPL's own price, earnings and insider-filing history. Tap one to see it in context.

02

Price and trading

The chart, today's range and how far the price has moved over each period.

2.0

Trend checks

3/4
  • Price above its 50-day average ›
    The price of $10.86 is 21.1% below the 50-day simple moving average of $13.77.
  • Price above its 200-day average ›
    The price is 20.1% above the 200-day simple moving average of $9.05.
  • 50-day average above the 200-day ›
    The 50-day average ($13.77) is 52.3% above the 200-day average ($9.05), the arrangement of a rising longer-term trend.
  • In the upper half of its 52-week range ›
    The price sits at 63% of its 52-week range, between $1.50 and $16.33.

REPL share price

Pick a period: each tab shows how far REPL has moved over it, to the last close.

Nov '25Jan '26Mar '26Jun '26Aug '26Oct '26
Start $4.67 Oct 16, 2025
Latest close $10.86 Oct 16, 2026
High $15.98 Sep 2, 2026
Low $1.70 Apr 13, 2026

Today's trading

Where REPL sits inside today's range and its 52-week range.

Day range 8.56% wide
$10.86
$10.81 $11.73
52-week range 63% of the way up
$10.86
$1.50 $16.33
Open
$11.73
Previous close
$11.75
Volume
1.71M
6% below average
Market cap
$1.02B
03

Fundamentals

Valuation against the sector, and the revenue and earnings behind it.

3.0

Valuation and quality checks

0/1
  • Beat estimates in most recent reports ›
    REPL beat the EPS estimate in 1 of its last 6 reports.

Key statistics

The headline figures for REPL.

Market Cap
1.02B
P/E Ratio
N/A (Negative EPS)
EPS (TTM)
-3.15
Dividend Yield
0.00%
52 Week High
16.33
52 Week Low
1.50

As of October 17, 2026, REPL trades at $10.86, with a market value of $1.02B and no P/E ratio (its trailing earnings are negative).

What the numbers say

CleaRank Financial AI's reading of REPL's valuation, growth and risks.

Valuation

Replimune Group, Inc. (REPL) cannot be valued on earnings, since its P/E is not meaningful because the company lost money over the last 12 months. To put the size in context, the company carries a market value of $1.0B, and its trailing earnings are -$3.15 a share.

Profitability is absent at this stage, with a net margin of 0.00% and an operating margin of 0.00%. Return on equity stands at -134.29%, which is below the sector median of 7.3%. Debt-to-equity is 1.06.

Earnings & Growth

Replimune beat expectations in the August 14, 2026 report by 6.49%, posting -$0.72 a share against an estimate of -$0.77. Even so, the stock slid 2.27% in the next session.

REPL has beaten the EPS estimate in 1 of its last 6 reports, but the share price still dropped in the first session after that beat. For the current fiscal year, analysts expect an average EPS of -$3.01, and -$1.82 for the year after.

Key risks

Day-to-day swings are the main risk to plan around, as REPL has moved 3.27% on an average session. The price is 33.50% below its 52-week high of $16.33. Insiders sold $2.6M of stock over the last 18 months and made no open-market purchases. Insider sales are often planned in advance or made to cover tax on vesting shares, so they are a weaker signal than buying.

REPL against the Healthcare sector

How REPL compares with the median Healthcare stock CleaRank tracks.

Return on equity 141.6 points below the median
REPL
-134.3%
Sector median
7.3%

Return vs XLV: Since May 6, 2025, REPL has gained 44.8% against a gain of 31.6% for XLV.

Performance against XLV

REPL and the Healthcare sector fund over the same days.

Jun '25Sep '25Dec '25Apr '26Jul '26Oct '26
REPL XLV

Revenue and earnings

How much REPL sells, and how much of it becomes profit.

Net income, 12 months
-$297M
FY2022FY2023FY2024FY2025FY2026
Revenue Net income

Loss-making: REPL lost $314M in FY2026.

Earnings reality check

Did REPL beat what analysts expected, and how did the stock react?

Beat the estimate
1 of 6
last 6 reports
Fell after a beat
1 of 1
first session after the report
Average surprise
-10.1%
actual EPS against the estimate
Avg. first-session move
-1.7%
the stock, after the report
EPS surprise
First-session move
Feb '25May '25Aug '25Nov '25Jun '26Aug '26

Earnings record: REPL beat the analyst estimate in 1 of the last 6 quarters.

Market reaction: The stock fell in the first session after 1 of those 1 beats, so a beat has not been enough on its own.

REPL earnings surprises and the stock's reaction
Report Estimate Actual Surprise First session 5 sessions
Aug 14, 2026after close -$0.77 -$0.72 +6.49% -2.27% -1.34%
Jun 29, 2026after close -$0.72 -$0.76 -5.56% -1.16% +2.77%
Nov 6, 2025after close -$0.79 -$0.90 -13.92% -2.24% +5.65%
Aug 7, 2025after close -$0.80 -$0.95 -18.75% -3.47% -2.37%
May 22, 2025after close -$0.69 -$0.82 -18.84% -4.68% +2.51%
Feb 12, 2025after close -$0.72 -$0.79 -9.72% +3.63% +3.77%

As of October 17, 2026, REPL has beaten the analyst EPS estimate in 1 of its last 6 reported quarters and fell in the first trading session after it; its latest report, on August 14, 2026, came in 6.49% above the estimate and the stock moved -2.27% in the first session.

The first session is the first full trading day on the news: the report day itself for a report before the open, the next day for one after the close. Surprise is actual EPS against the consensus estimate.

04

AI analysis and technicals

CleaRank's score and reasoning, the indicators behind it, and what the price moves with.

4.0

Momentum checks

1/3
  • RSI not overbought or oversold ›
    The 14-day RSI is 31.9, showing bearish momentum without being oversold.
  • RSI above 50 ›
    An RSI of 31.9 is below the 50 midpoint, so sellers have had the upper hand over the last 14 days.
  • MACD line above zero ›
    The MACD line is negative, so the 12-day average is below the 26-day average.

CleaRank AI analysis of REPL

The score, the reasoning behind it, and what could move the price next.

Company's health
3/5
12-month analyst target
$19.50
+79.56% above price · median of 8 analysts
AI analyst consensus
49/100
Hold
What the AI sees

Replimune Group, Inc. (REPL) is caught between its two moving averages. At $10.86 the stock trades 20.06% above its 200-day average of $9.05 but 21.15% below its 50-day average of $13.77. That 50-day average sits 52.26% above the 200-day, and the price stands at 63% of the way across its 52-week range, which runs from $1.50 up to $16.33.

The recent dip looks smaller once the longer record is in view. Over the past month the price slid 16.20%, yet over three months it climbed 6.16% and over the past year it gained 132.55%. Momentum is weak for now: the 14-day RSI sits at 31.9, in the bearish zone but not yet oversold, and the MACD line is negative.

Catalysts
Rewards
  • Analyst upgrade ›

    Wedbush upgraded it to Outperform from Neutral on August 7, 2026.

    Source: Analyst action, Wedbush, August 7, 2026
  • Analyst upgrade ›

    Leerink Partners upgraded it to Outperform from Market Perform on August 4, 2026.

    Source: Analyst action, Leerink Partners, August 4, 2026
Risks
  • Earnings beat ›

    The August 14, 2026 report beat the EPS estimate by 6.49%, and the share price fell 2.27% in the first session after it.

    Source: Earnings report, August 14, 2026
ProTips
  1. The two nearest levels matter most: the 20-day EMA at $12.66 sits above the price, and the 200-day SMA at $9.05 sits below it.
  2. The 14-day RSI reads 31.9, in the bearish zone, with the MACD line negative; readings above 70 or below 30 mark stretched momentum.
  3. The share price fell 2.27% in the first session after the August 14, 2026 report. REPL has beaten estimates in 1 of the last 6 reports.
Market outlook

The trend is mixed: REPL is above its 200-day average at $9.05 but below its 50-day average at $13.77. A close above the 50-day would turn both signals up, and a close below the 200-day would turn both down. In the meantime the price sits between the 200-day SMA ($9.05) underneath and the 20-day EMA ($12.66) overhead.

The RSI sits in the bearish band, which leans against a quick recovery.

Technical indicators

Momentum and trend for REPL, from its daily closes.

Technical rating Bearish 1 of 4 signals bullish
  • RSI Bearish
  • SMA cross Bullish
  • Price vs SMA Bearish
  • MACD Bearish
Momentum Bearish
31.914-day RSI
Oversold <30 Neutral Overbought >70
MACD (12, 26) -0.467 Bearish
Trend Golden cross
-21.1%price against the 50-day average
200-day $9.045 50-day $13.77 Price $10.86
Price against the 200-day +20.1% Bearish

As of October 17, 2026, with REPL at $10.86, its 14-day RSI is 31.9 (showing bearish momentum without being oversold), its 50-day simple moving average is $13.77 and its 200-day is $9.05.

Calculated by CleaRank on daily closes as of October 17, 2026: Wilder's 14-day RSI, 50- and 200-day simple moving averages, MACD line (12, 26).

What REPL moves with

Correlation of daily returns over one year: +1 moves in step, 0 has no link, -1 moves the opposite way.

-1 0 +1
S&P 500 (SPY) +0.03 Weak
Nasdaq 100 (QQQ) +0.05 Weak
Bitcoin (BTC) -0.02 Weak
Gold (XAU) +0.03 Weak

As of October 17, 2026, REPL's 1-year correlation of daily returns is +0.03 with S&P 500 (SPY), +0.05 with Nasdaq 100 (QQQ), -0.02 with Bitcoin (BTC) and +0.03 with gold (XAU).

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05

What Wall Street expects

The analysts' target range and how their ratings split.

5.0

Analysts checks

3/3
  • Most analysts rate it a buy ›
    7 of 8 analysts rate it a buy or strong buy, 0 a hold and 1 a sell.
  • Median target above the price ›
    The median 12-month target of $19.50 is 79.6% above the price.
  • More buy ratings than three months ago ›
    7 of 8 rate it a buy now, against 4 of 8 three months ago.

REPL Wall Street View

12-month price targets

Low $14.00 Median $19.50 (+79.6%) High $24.00

The price, $10.86, sits below every analyst's target.

Ratings

Buy 7 Hold 0 Sell 1 3 months ago: 4 of 8 buy

Recent rating actions

Recent analyst rating actions on REPL
Date Firm Action Rating
Aug 26, 2026 JP Morgan Maintains Overweight
Aug 7, 2026 JP Morgan Maintains Overweight
Aug 7, 2026 Wedbush Upgrade Outperform
Aug 4, 2026 Leerink Partners Upgrade Outperform
Jul 31, 2026 Wedbush Maintains Neutral
Jul 31, 2026 Cantor Fitzgerald Upgrade Overweight

As of October 17, 2026, 8 Wall Street analysts cover REPL: 7 rate it a buy or strong buy, 0 a hold and 1 a sell or strong sell. Their 12-month price targets range from $14.00 to $24.00, with a median of $19.50, 79.6% above the price of $10.86.

Source: TwelveData analyst consensus. Targets and ratings belong to the analysts, not to CleaRank.

06

A trade plan, if you want one

Entry, stop and target levels from the moving averages and recent volatility. Educational, not advice.

REPL trade plan

Entry, stop and target levels, sized to your account. Change the bias or the risk and every level updates.

Your bias
Risk per trade 2%
Conservative Aggressive
Portfolio value
$
Position size: Enter portfolio size →

Entry Strategies pick an entry style

Conservative
$10.75
Slight discount to current
Wait for small dip
Aggressive
$10.86
At current price
Enter now if confident

Risk management

Stop loss
$9.371
Max loss
-12.8%
Volatility-adjusted stop Set from the RSI (31.9) and recent volatility.

Profit targets (Based on Conservative Entry)

Target 1
$11.07
+3% (Conservative) +2.0% (Aggressive)
Target 2
$11.29
+5% (Conservative) +4.0% (Aggressive)
Target 3
$11.61
+8% (Conservative) +6.9% (Aggressive)

REPL moves about 3.3% a day on average, so a stop can fill well past its level. Educational levels, not financial advice; the full disclaimer is at the foot of the page.

Risk profile

How much REPL tends to move, against the market and on its own.

Daily volatility
3.27%
30-day standard deviation
52-week range
$10.86
$1.50 63% of the way up $16.33

Compare REPL

Put REPL side by side with other stocks and benchmarks.

07

The long record

REPL's worst falls and recoveries, what $10,000 became, and which months have been kind to it.

7.0

Track record checks

0/4
  • Average daily move under 2% ›
    The price has moved 3.27% on an average day (30-day standard deviation of daily returns).
  • Recovered from its worst fall ›
    The worst fall was 96.7%, from November 2020 to April 2026; the price is still 79.0% below that peak.
  • Most 1-year holds ended higher ›
    46% of 1-year holding periods in the last 8 years ended with a gain.
  • Beat the S&P 500 since the chart begins ›
    $10,000 invested in July 2018 is now worth $7,163.59, against $30,885 in the S&P 500 (SPY).

REPL Drawdowns & Recovery

Worst fall, last 8 years
-96.7%
November 2020 to April 2026
Recovery
Not yet
still 79.0% below the November 2020 peak
From the 8-year high
-79.0%
highest close, November 2020
1-year holds that gained
46%
of every 1-year window

As of October 17, 2026, REPL's worst peak-to-trough fall over the last 8 years with dividends reinvested was -96.7% (November 2020 to April 2026); it is still 79.0% below that peak, and 46% of 1-year holding periods ended with a gain.

From weekly closing values with dividends reinvested. A drawdown is the fall from the highest value reached so far to a later low.

Growth of $10,000

What $10,000 put into REPL in July 2018 is worth now, against the same amount in the S&P 500.

REPL today
$7,163.59
from $10,000 in July 2018, dividends reinvested
S&P 500 today
$30,885
the same $10,000 in SPY
Behind the index by
$23,721
0.2x the index result
Total change
-28%
0.7x the starting amount
2020202220242026
REPL S&P 500 (SPY)

Against the market: REPL trailed the S&P 500 over this period: $7,163.59 against $30,885.

A $10,000 investment in REPL in July 2018 would be worth about $7,164 today with dividends reinvested, compared with about $30,885 for the same investment in the S&P 500 benchmark (also with dividends reinvested).

Seasonal patterns

Which calendar months have been kind to REPL, and which have not.

Jan3/8 upFeb4/8 upMar2/8 upApr3/8 upMay4/8 upJun8/8 upJul2/8 upAug4/9 upSep2/9 upOct6/8 upNov4/8 upDec2/8 up

Strongest month, June: an average of +35.35%, up in 8 of 8 years.

Weakest month, April: an average of -11.64%, up in 3 of 8 years.

This month, October: has averaged +28.26%, up in 6 of 8 years. Past seasonality does not repeat on schedule.

Over the last 9 years, REPL's strongest calendar month has been June (average +35.35%, up in 8 of 8 years) and its weakest April (average -11.64%, up in 3 of 8 years).

Average return for each calendar month over the last 9 years, from weekly closing prices with dividends included.

08

Long-term scenarios

Thousands of simulated paths from the price history. A range of outcomes, not a forecast.

Monte Carlo projection

Thousands of simulated paths for $10,000 in REPL, from its own past volatility. The shaded area holds 80% of them.

Downside, 2036
$1,429
10th percentile
Base case, 2036
$10,844
median path
Upside, 2036
$82,267
90th percentile
202620282030203220342036
Upside (90th) Base case (median) Downside (10th) 10th to 90th percentile

CleaRank's 10-year Monte Carlo simulation projects that a $10,000 investment in REPL today could grow to about $10,844 by 2036 in the base case, with a 90th-percentile outcome near $82,267 and a 10th-percentile outcome around $1,429. Projections are statistical simulations, not guarantees.

REPL Stock Price Prediction: 2030

The same simulation in share prices, year by year.

Price today
$10.86
Base case, 2030
$11.22
1.0x over 4 years
Range, 2030
$3.11 to $40.41
10th to 90th percentile

CleaRank's simulation projects a price near $11.22 for REPL by 2030 in the base case, from $10.86 today (1.0x over 4 years). The 10th-percentile path ends near $3.11. These are outcomes of a Monte Carlo simulation run on REPL's historical return distribution, not price targets, and they assume no dividends are reinvested.

REPL simulated price paths by year
Year 10th percentile Base case 90th percentile range base today
2027 $5.77 $10.95 $20.78
2028 $4.46 $11.04 $27.32
2029 $3.67 $11.13 $33.76
2030 $3.11 $11.22 $40.41
2031 $2.70 $11.31 $47.39

Method: a lognormal simulation of REPL's own volatility and capped historical trend, re-run daily; base case is the median path, the outer columns the 10th and 90th percentiles.

09

Insider trading

What the people running the company have bought and sold.

REPL insider trading

Shares the company's directors and officers bought and sold, from their own filings.

Bought
None
no open-market buys
Sold
$2.6M
24 open-market sales
Insiders filing
7
over the last 18 months
Average trade
$108K
buys and sales together

Month by month

Open-market purchases above the line, sales below.

May '25Aug '25Nov '25Feb '26May '26Aug '26Oct '26

Insider buying: No insider bought REPL shares on the open market in the last 18 months. Sales are often planned in advance or cover tax on vesting shares, so they say less than purchases would.

As of October 17, 2026, REPL insiders reported 24 open-market sales worth $2.6M and no open-market purchases over the last 18 months; grants and option exercises are not counted.

Insider transactions in REPL
Date Insider Type Shares Value
Aug 20, 2026
Philip Astley-Sparke
Director
Grant 50.0K -
Aug 17, 2026
Emily Luisa Hill
Chief Financial Officer
Sell 9.3K $132.2K
Aug 10, 2026
Sushil Patel
Chief Executive Officer
Sell 39.3K $510.3K
Aug 10, 2026
Emily Luisa Hill
Chief Financial Officer
Sell 11.4K $148.5K
Aug 10, 2026
Konstantinos Xynos
Officer
Sell 11.4K $148.5K
Aug 10, 2026
Andrew Schwendenman
Officer
Sell 7.6K $99.0K
Jun 1, 2026
Christopher Sarchi
Officer
Sell 12.0K $110.9K
May 18, 2026
Sushil Patel
Chief Executive Officer
Sell 37.3K $189.6K
May 18, 2026
Philip Astley-Sparke
Director
Sell 17.7K $89.7K
May 18, 2026
Konstantinos Xynos
Officer
Sell 14.0K $71.2K
Page 1 of 4

Source: TwelveData, from SEC Form 4 filings

10

Questions people ask

Answered from the figures on this page, as of October 17, 2026.

Frequently Asked Questions

Is Replimune Group, Inc. (REPL) a buy right now?
CleaRank rates REPL Hold, on a model score of 49/100. The biggest support is the analysts' outlook: 7 of 8 analysts rate it a buy and the median target is 79.6% above the price. Against that, momentum weighs on the score, as the 14-day RSI of 31.9 is in the bearish zone and the MACD line is negative. This describes the data on this page and is not a personal recommendation.
How has Replimune Group, Inc. (REPL) performed over the past year?
The stock rose 132.55% across the past year. Looking at shorter spans, it climbed 6.16% over three months but dropped 16.20% in the last month. The price is currently 33.50% below its 52-week high of $16.33.
What are the key price levels for REPL?
The nearest levels above the price are the 20-day EMA at $12.66 and the 50-day SMA at $13.77. Below the price, the levels are the 200-day SMA at $9.05 and the 52-week low at $1.50.
Does REPL have a P/E ratio?
REPL's P/E is not meaningful because the company lost money over the last 12 months, so there is no usable earnings multiple.
What do Wall Street analysts think of REPL?
Of the 8 analysts covering REPL, 7 rate it buy, 0 hold and 1 sell. Their median 12-month target is $19.50, 79.6% above the current price.
How often has REPL beaten earnings estimates?
REPL beat the EPS estimate in 1 of the last 6 reports in our data. The share price fell in the first session after 1 of those 1 beats.
How volatile is REPL?
On an average day REPL's price moves 3.27%, based on the 30-day standard deviation of daily returns.
Are REPL insiders buying or selling?
Insiders sold $2.6M of stock over the last 18 months and bought none on the open market. Because sales are often planned ahead or made to cover tax on vesting shares, they tell an investor less than purchases would.
What is the 52-week range of REPL?
Over the past 52 weeks REPL has traded between $1.50 and $16.33. At $10.86 the stock sits at 63% of that span, 624.00% above the low and 33.50% below the high.
Is REPL in an uptrend?
Not clearly. Replimune Group, Inc. (REPL) trades at $10.86, above its 200-day but below its 50-day moving average ($9.05 and $13.77). Its 14-day RSI on daily closes is 31.9, showing bearish momentum without being oversold.

Disclaimer: CleaRank.com is a financial data and analytics provider, not a registered investment advisor, broker-dealer, or financial regulatory body. The stock analysis, trade plans, and AI-generated signals presented for REPL are for educational and informational purposes only and do not constitute financial advice, investment recommendations, or an offer to buy or sell any securities. All trade setups and performance metrics shown are hypothetical, hindsight-based, and simulated. They do not represent actual trades made by CleaRank or its affiliates. Stock prices can be volatile and are subject to market, economic, and company-specific risks. Market data is provided "as-is" and may be delayed by 15 minutes or more. We do not guarantee the accuracy, completeness, or timeliness of any data. You should never invest money you cannot afford to lose. Past performance does not guarantee future results. Consult a qualified financial advisor before making any investment decisions. Analysis generated on October 17, 2026.

Disclaimer:

Engaging in financial markets carries significant risk of total capital loss. Markets are volatile, unpredictable, and past success does not guarantee future results. Never invest funds you cannot afford to lose. CleaRank does not offer financial, investment, or advisory services. We provide no recommendations, endorsements, or guarantees regarding market outcomes. You alone are responsible for your decisions.

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