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As of September 12, 2026, Replimune Group, Inc. (REPL) trades at $12.92. CleaRank Financial AI rates it Sell with a fair value of $12.92, in line with the current price. Wall Street's consensus target is $19.50 across 8 analysts. RSI at 33 is in neutral territory, and the price is above its 50-day average of $12.45.

Replimune Group, Inc. (REPL)

Replimune Group, Inc. NASDAQ

$12.92 -0.3200 (-2.42%)
At close: Sep 11, 4:00 PM EDT
AI Analyst Consensus
Sell
21 / 100
Replimune Group, Inc. (REPL) is currently trading at $12.92, with its price above its 50-day and 200-day moving averages ($12.45 and $8.69) but below its 20-day EMA, indicating mixed short-term technical signals. The company has experienced significant insider selling totaling $2.6 million in the past 43 transactions, with no reported insider purchases. This net selling pressure, coupled with a negative EPS of -$3.15, raises concerns about the company's near-term financial health and investor confidence, despite a generally positive sentiment from Wall Street analysts.

REPL Price Analysis

Market Metrics

Open
$13.33
Day Range
$12.40 to $13.74
Prev Close
$13.24
Volume
4.08M
52-Week Range
$1.50 to $16.33
Market Cap
$1.22B

Peer Benchmarking

Valuation vs Sector (Healthcare)

Performance vs XLV

Sector Position Analysis

REPL Financial Performance

Revenue vs. Earnings

Annual

Quarterly

Earnings Reality Check

Analysis: In the last 5 quarters, REPL beat estimates 4 times. However, the stock fell 3 times the next day. This suggests positive news is often "priced in" or investors are selling the news.

REPL Analysis

Company's Health 2/5
AI Technical Analysis Sell
Replimune Group, Inc. (REPL) is trading above its 50-day and 200-day moving averages ($12.45 and $8.69), suggesting a longer-term bullish trend. However, the stock is currently below its 20-day exponential moving average, indicating some short-term weakness. The Relative Strength Index (RSI) is at 33.33, signaling bearish momentum. Volume has been notably high, with the latest volume at 4,084,167, more than double the average volume of 2,041,557, suggesting significant investor interest and potential for volatility.
ProTips
  • Monitor insider transactions closely; the recent $2.6 million in net selling by insiders warrants significant attention and could signal a lack of confidence.
  • The RSI is currently below 50, indicating bearish momentum. Investors should watch for a potential bounce if the RSI moves back above 50, but the current trend is negative.
  • Given the negative EPS and mixed earnings performance, investors should consider the company's cash burn rate and long-term funding strategy.
Key Catalysts
Bearish Significant Insider Selling

Insiders have sold $2.6 million worth of stock across 43 transactions, with no reported insider purchases, indicating a potential lack of confidence in future performance.

Source: Insider Transactions
Bearish Negative EPS Trend

Replimune Group, Inc. has a current EPS of -$3.15, and recent earnings reports show inconsistent performance with a persistent negative EPS trend, raising concerns about profitability.

Source: Earnings Reports
Bullish Positive Analyst Sentiment

The majority of Wall Street analysts maintain a 'Buy' rating, with a median price target of $19.50, suggesting an expected upside of 50.9% from the current price.

Source: Wall Street Analysts
Bullish Strong Forward Revenue Growth Projection

Next year's revenue estimates show a projected growth of 490.00% to $50.2 million, indicating significant potential for future top-line expansion.

Source: Revenue Estimates
Market Outlook
The outlook for Replimune Group, Inc. (REPL) is cautiously bearish, primarily due to significant insider selling and a negative EPS. While Wall Street analysts maintain a 'Buy' consensus with a median price target of $19.50, the current price action and insider activity suggest potential headwinds. The company's forward revenue estimates show strong projected growth, but this must be weighed against the current profitability challenges and the signal from insider transactions.

Key Statistics

Market Cap 1.22B
P/E Ratio N/A (Negative EPS)
EPS (TTM) -3.15
Dividend Yield 0.00%
52 Week High 16.33
52 Week Low 1.50
Replimune Group, Inc. (REPL) exhibits a negative EPS of -$3.15, making traditional P/E ratio analysis inapplicable. The company's revenue growth is not provided, but forward revenue estimates for next year show a substantial projected increase of 490.00% to $50.2 million, albeit with a capped average that suggests potential outlier skew. The current price of $12.92 is below the median Wall Street price target of $19.50, implying a potential upside of 50.9%, but this is contrasted by significant insider selling.

Earnings & Growth Analysis

Replimune Group, Inc. (REPL) most recently reported an EPS of -$0.72, beating the estimated -$0.77 by 6.49%, though the stock saw a -2.27% price change. Prior to this, the company missed estimates in the June 2026 quarter. The March 2026 quarter showed a significant EPS beat of 11.86%, but the stock price reacted negatively. Overall, earnings performance has been inconsistent, with a mix of beats and misses, and a persistent negative EPS trend.

Key Risks

The primary risk for Replimune Group, Inc. (REPL) stems from significant insider selling totaling $2.6 million, indicating a lack of confidence from management. The company also carries a negative EPS of -$3.15, raising concerns about its profitability and financial sustainability. While Wall Street maintains a 'Buy' consensus, the bearish technical momentum and insider activity present considerable downside risks.

Technical Indicators i

RSI (14) 33.33
MACD 0.41
SMA 50 12.45
SMA 200 8.69
Technical Rating Bullish
RSI
Bearish
SMA Cross
Bullish
Price vs SMA
Bullish
MACD
Bullish
Golden Cross in effect with the 50-day SMA ($12.45) above the 200-day SMA ($8.692), price action is firmly bullish above key moving averages.

Market Correlations

How this stock moves relative to other assets

Based on 1 year of daily price data. Correlations may vary over different time periods.

S&P 500 (SPY) +0.03
Weak correlation
Nasdaq 100 (QQQ) +0.05
Weak correlation
Bitcoin (BTC) -0.05
Weak correlation
Gold (XAU) +0.02
Weak correlation
Check Custom Correlation

REPL Trade Plans

Specific entry, exit, and risk management levels

Select Your Trade Bias
Risk Tolerance
Conservative 2% Aggressive
Portfolio Value
$
Position Size: Enter portfolio size →

🔴 SHORT ENTRY (click to switch)

CONSERVATIVE
$13.18
2% above current price
Lower risk, wait for rally
AGGRESSIVE
$12.92
Short at current price
Higher risk, chasing the move

Risk Management

STOP LOSS
$15.31
MAX LOSS
-16.2%
Volatility-Adjusted Stop Loss
Calculated based on RSI (33.3) and current market volatility

Profit Targets (Based on Conservative Entry)

TARGET 1
$12.52
-5% (Conservative)
-3.1% (Aggressive)
TARGET 2
$11.86
-10% (Conservative)
-8.2% (Aggressive)
TARGET 3
$11.20
-15% (Conservative)
-13.3% (Aggressive)
Consider scaling out: Take 50% profit at Target 1, 30% at Target 2, let 20% run to Target 3
⚠️ High-Volatility Risk Disclaimer
REPL is classified as a high-volatility asset (Daily Vol: 5.12%). Aggressive price swings can lead to rapid capital loss. Liquidity risks may prevent exiting trades at desired prices. This AI-generated analysis is for educational purposes only and is not financial advice. Generated on September 12, 2026.

Growth of $10,000

A $10,000 investment in REPL in July 2018 would be worth about $8,522 today, compared with about $27,327 for the same investment in the S&P 500 benchmark.

Compare with Another Ticker

Monte Carlo Projection (10yr)

CleaRank's 10-year Monte Carlo simulation projects that a $10,000 investment in REPL today could grow to about $12,218 by 2036 in the base case, with a bull case near $92,695 and a bear case around $1,610. Projections are statistical simulations, not guarantees.

REPL Stock Price Prediction: 2030

CleaRank's simulation projects a price near $14.00 for REPL by 2030 in the base case, from $12.92 today (1.1x over 4 years). The downside path ends near $3.89. These are outcomes of a Monte Carlo simulation run on REPL's historical return distribution, not price targets, and they assume no dividends are reinvested.

REPL simulated price paths by year
Year Downside (10th pct) Base case Upside (90th pct)
2027 $6.94 $13.18 $25.02
2028 $5.43 $13.45 $33.28
2029 $4.52 $13.72 $41.63
2030 $3.89 $14.00 $50.43
2031 $3.41 $14.28 $59.85
2032 $3.03 $14.57 $70.01
2033 $2.73 $14.87 $81.00
2034 $2.48 $15.17 $92.90
2035 $2.26 $15.47 $106
2036 $2.08 $15.79 $120

Method: 10,000 simulated price paths using REPL's historical volatility and drift, re-run daily. The base case is the median path; the two outer columns are the 10th and 90th percentile outcomes, which widen with time because uncertainty compounds. Simulations are not guarantees, and past volatility does not predict future returns. This is analysis, not investment advice.

People Also Watch

REPL Insider Trading Analysis

Source: SEC Form 4
Bought
None
No open-market buys
Sold
$2.6M
24 Transactions
Insiders
7
Active Traders
$ Avg Transaction
$107.7K
Moderate size
Recent insider transactions in REPL
Date Insider Type Shares Value
Dec 9, 2020
RHODES JASON P
Director
Sell 217.4K $10.0M
Dec 22, 2020
COFFIN ROBERT
President
Sell 220.0K $8.8M
Dec 14, 2020
RHODES JASON P
Director
Sell 103.7K $4.5M
Jul 9, 2020
COFFIN ROBERT
President
Sell 169.8K $3.8M
Sep 17, 2021
OMEGA FUND IV, LP.
Beneficial Owner of more than 10% of a Class of Security
Sell 100.0K $3.3M
Dec 17, 2020
RHODES JASON P
Director
Sell 65.0K $2.7M
Jan 22, 2021
COFFIN ROBERT
President
Sell 60.0K $2.7M
Jan 19, 2021
ESPOSITO PAMELA
Officer
Sell 55.0K $2.4M
Jan 19, 2021
ESPOSITO PAMELA
Officer
Sell 55.0K $2.4M
Jan 19, 2021
ASTLEY-SPARKE PHILIP
Chief Executive Officer
Sell 50.0K $2.2M

Frequently Asked Questions

What is Replimune Group, Inc.'s current stock price and outlook?
Replimune Group, Inc. (REPL) is currently trading at $12.92. The outlook is mixed, with a 'Buy' consensus from Wall Street analysts and a median price target of $19.50, but tempered by significant insider selling and bearish technical momentum.
Is Replimune Group, Inc. stock a buy or sell?
Based on the current data, the consensus rating is 'Sell' with a score of 18. While Wall Street analysts largely rate it a 'Buy', significant insider selling and negative EPS trends suggest caution.
What are the key risks facing Replimune Group, Inc.?
The primary risks include substantial insider selling totaling $2.6 million, a negative EPS of -$3.15, and bearish momentum indicated by the RSI. These factors outweigh the positive sentiment from Wall Street analysts.
How has Replimune Group, Inc. performed in recent earnings reports?
Replimune Group, Inc. (REPL) recently beat EPS estimates by 6.49% in its latest report, but the stock price declined. Prior quarters have shown inconsistent performance with both beats and misses, and a persistent negative EPS trend.
What is the technical outlook for Replimune Group, Inc. stock?
Technically, REPL is trading above its 50-day and 200-day moving averages ($12.45 and $8.69) but below its 20-day EMA. The RSI is in bearish territory at 33.33, indicating bearish momentum, despite the longer-term moving average support.
What is Replimune Group, Inc.'s revenue growth projection?
However, forward estimates for next year project significant growth of 490.00% to $50.2 million, though this average may be skewed by outliers.
What is Replimune Group, Inc.'s stock forecast for 2030?
According to Monte Carlo simulations, Replimune Group, Inc.'s stock forecast for 2030 shows a base case price of $14, with a downside projection of $3.89 and an upside projection of $50.43. These are simulation outcomes, not guarantees.

Disclaimer: CleaRank.com is a financial data and analytics provider, not a registered investment advisor, broker-dealer, or financial regulatory body. The stock analysis, trade plans, and AI-generated signals presented for REPL are for educational and informational purposes only and do not constitute financial advice, investment recommendations, or an offer to buy or sell any securities. All trade setups and performance metrics shown are hypothetical, hindsight-based, and simulated. They do not represent actual trades made by CleaRank or its affiliates. Stock prices can be volatile and are subject to market, economic, and company-specific risks. Market data is provided "as-is" and may be delayed by 15 minutes or more. We do not guarantee the accuracy, completeness, or timeliness of any data. You should never invest money you cannot afford to lose. Past performance does not guarantee future results. Consult a qualified financial advisor before making any investment decisions. Analysis generated on September 12, 2026.