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Head-to-head · Stock vs Stock

Eli Lilly and Company vs AbbVie

Stock·NYSE

Eli Lilly and Company LLY

$1,257.03 ▲ 0.43%
Buy
78 / 100 AI score
Full LLY analysis →
vs

Stock·NYSE

AbbVie Inc. ABBV

$285.42 ▲ 0.71%
Buy
69 / 100 AI score
Full ABBV analysis →
01

The short version

How LLY and ABBV compare today, and what CleaRank Financial AI makes of it.

The verdict

LLY and ABBV on the figures that matter most, and which one CleaRank Financial AI prefers today.

CleaRank Financial AI favours LLY
LLY ABBV
78/100 AI score 69/100
+56.6% 1-year change +24.3%
25.6% Volatility (30d, yearly) 18.6%
68.6 RSI (14-day) 71.1
42.0x P/E ratio 80.1x
0.53% Dividend yield 2.42%
The verdict
Eli Lilly and Company (LLY) secures a win over AbbVie Inc. (ABBV) primarily driven by its superior profitability and stronger recent earnings performance. While both companies operate in the pharmaceutical sector and present compelling investment cases, LLY's significantly higher net profit margin and return on equity, coupled with consistent, substantial earnings beats, position it as the more attractive asset for investors focused on operational efficiency and growth. LLY's valuation metrics, though appearing higher on a P/E basis, are supported by its exceptional growth trajectory and profitability, which ABBV does not match. Technical indicators also favor LLY, showing strong momentum without being excessively overbought, whereas ABBV is nearing overbought territory. The key differentiator lies in LLY's strong drug pipeline and execution, translating into superior financial performance.
Key difference
The decisive factor separating Eli Lilly and Company (LLY) from AbbVie Inc. (ABBV) is LLY's demonstrably superior profitability and consistent, high-magnitude earnings beats. LLY's net profit margin and return on equity are significantly higher, showcasing exceptional operational efficiency and value creation.
Outlook
The outlook for Eli Lilly and Company (LLY) remains highly positive, driven by its strong drug pipeline and consistent execution, which should support continued revenue growth and profitability. We anticipate LLY will maintain its upward trajectory, potentially reaching new highs as its key drugs gain market share. AbbVie Inc. (ABBV) faces a more mixed outlook. While it is expected to continue generating solid cash flows and maintain its dividend, the company must successfully navigate patent expirations and demonstrate growth from its newer assets. Investors should watch for pipeline successes and strategic acquisitions to offset potential revenue declines from older products.
02

Price, side by side

Both prices on one chart, rebased so the moves compare directly.

Rebased price

Both start at 0% on the first day of the period you pick, so the two lines compare directly.

Nov '25Jan '26Mar '26Jun '26Aug '26Oct '26
LLY ABBV

Over 1 year: LLY gained 52.1% and ABBV gained 26.2%, a gap of 25.9 points in LLY's favour.

03

Valuation and profitability

What each costs relative to its earnings and sales, and how much of its revenue it keeps.

Valuation and profitability

What each costs against its earnings and sales, and how much of its revenue it keeps.

Valuation

Lower multiples mean you pay less for each dollar of earnings or sales.

LLY ABBV
$1.12T Market cap $504.4B
42.0x P/E ratio 80.1x
14.0x Price / sales 7.8x
32.9x Price / book N/A
27.9x EV / EBITDA 18.4x

Profitability

How much of each dollar of revenue becomes profit, and how hard the capital works.

LLY ABBV
+47.7% Revenue growth (quarter, y/y) +10.2%
33.5% Net margin 9.7%
102.3% Return on equity -129.7%
20.4% Return on assets 10.5%
1.62 Debt / equity -0.12
On valuation
Eli Lilly and Company (LLY) trades at a P/E ratio of 42.01, which is lower than AbbVie Inc.'s (ABBV) P/E of 80.06, suggesting LLY is more attractively valued on this metric. However, LLY's P/E is justified by its significantly higher revenue growth of 47.7% compared to ABBV's 10.2%. LLY's market capitalization of $1.12 trillion dwarfs ABBV's $504 billion, reflecting its larger scale and market dominance. While ABBV's price is closer to its 52-week high, LLY's price is also trading robustly above its 200-day simple moving average ($1079.91), indicating a strong uptrend. LLY's higher valuation multiples are supported by its superior growth and profitability, making its current price a more compelling investment relative to its earnings potential.
On profitability
Eli Lilly and Company (LLY) exhibits significantly superior profitability compared to AbbVie Inc. (ABBV). LLY boasts a net profit margin of 33.53% and a return on equity of 102.29%, indicating exceptional efficiency in converting revenue into profit and strong returns for shareholders. Its return on assets at 20.36% further confirms its operational effectiveness. While ABBV's return on assets is a respectable 10.51%, it falls short of LLY's performance. LLY's profitability metrics are a clear advantage.

Earnings reality check

Each company's record against analyst estimates, and how its shares reacted.

LLY

Beat the estimate in 6 of 7 reports; fell the next session after 2 of those beats.

Surprise
Next session
Feb '25Aug '25Feb '26Aug '26

ABBV

Beat the estimate in 4 of 4 reports; fell the next session after 2 of those beats.

Surprise
Next session
Jul '25Oct '25Feb '26Jul '26
04

Momentum and sentiment

The indicators behind each AI score, side by side.

Momentum and sentiment

The indicators behind each AI score. Above the 50-day and 200-day averages is an uptrend.

LLY ABBV
78/100 AI score 69/100
68.6 RSI (14-day) 71.1
+6.5% Price against 50-day average +8.8%
+16.4% Price against 200-day average +22.0%
Technicals
Eli Lilly and Company (LLY) shows strong upward momentum, with its RSI at 68.56, indicating firm momentum without being excessively overbought. The MACD at 15.46 suggests a bullish trend, and the stochastic oscillator at 86.97 is high but within a range that can persist in strong uptrends. LLY's price is trading well above its 20-day EMA ($1185.80), 50-day SMA ($1180.35), and 200-day SMA ($1079.91), confirming a strong uptrend. AbbVie Inc. (ABBV) also displays strong momentum, with an RSI of 71.06 nearing overbought territory and a stochastic reading of 82.17 also indicating high momentum. Its MACD at 6.04 is positive but less pronounced than LLY's. ABBV's price is trading above its 20-day EMA ($271.93), 50-day SMA ($262.45), and 200-day SMA ($233.95), confirming an uptrend, though LLY's technical picture appears stronger and less stretched.
Sentiment
Analyst sentiment strongly favors Eli Lilly and Company (LLY), with a consensus rating of 'Strong Buy' from 6 analysts and 'Buy' from 19, totaling 25 positive ratings out of 30. The median analyst target price of $1385 suggests significant upside potential from its current price. AbbVie Inc. (ABBV) also garners positive analyst attention, with 8 'Strong Buy' and 16 'Buy' ratings from 30 analysts. However, its median target price of $285 is very close to its current trading price, indicating less perceived upside by the analyst community.
05

Risk and practical tips

How much each moves, and what to watch if you hold either.

Risk

How much each moves, and how much return each has paid for that risk.

LLY ABBV
25.6% Volatility (30d, yearly) 18.6%
0.45 Beta against the S&P 500 0.23
0.56 Sharpe ratio 0.67
Risk
For Eli Lilly and Company (LLY), key risks include the potential for pipeline failures in its extensive drug development program and increasing competition in its key therapeutic areas. Regulatory hurdles or unexpected side effects from its blockbuster drugs could also negatively impact its valuation. The company's high valuation, while supported by growth, also means it has less room for error. AbbVie Inc. (ABBV) faces significant risks related to patent expirations for its key drugs, particularly Humira, and the increasing competition in the immunology and oncology markets. Its substantial debt load and negative return on equity also present financial risks. Also, the company's reliance on a few key products makes it vulnerable to market shifts and competitive pressures.
ProTips
  1. Consider LLY for its superior operational efficiency and growth, supported by consistent earnings outperformance.
  2. Monitor ABBV's progress in diversifying its revenue streams beyond its key legacy products to mitigate patent cliff risks.
  3. While ABBV offers a higher dividend yield, LLY's stronger profitability and growth may offer better total return potential over the long term.
06

Long-term scenarios

Simulated paths from each price history. A range of outcomes, not a forecast.

Simulated growth of $10,000

Thousands of paths from each price history: the median and the 90th percentile for each.

202620282030203220342036
LLY median LLY 90th ABBV median ABBV 90th
LLY ABBV
$8,607 Downside, 2036 (10th) $8,649
$29,541 Base case, 2036 (median) $25,134
$101,392 Upside, 2036 (90th) $73,041

In the median simulated path, $10,000 in LLY grows to about $29,500 and $10,000 in ABBV to about $25,100 by 2036. The paths come from each asset's own historical volatility and trend; they are statistical outcomes, not forecasts.

07

Trade plans for both

Entry, stop and target levels from each moving average and its volatility. Educational, not advice.

Actionable Trade Plans

Compare entry, exit, and risk management levels for both assets

Select Your Trade Bias
Risk Tolerance
Conservative 3% Aggressive
Portfolio Value
$ ✎
Position Size: $200 - $300 per asset
LLY
Current: $1,257.03
ENTRY ZONES
$1,194.18
$1,257.03
RISK MANAGEMENT
STOP LOSS
$1,158.35
MAX LOSS
-3%
Volatility-Adjusted Stop Loss
Calculated based on volatility and technical support levels.
Profit Targets (Based on Conservative)
+5% from current
$1,319.88
+10% from current
$1,382.73
+15% from current
$1,445.58
ABBV
Current: $285.42
ENTRY ZONES
$271.15
$285.42
RISK MANAGEMENT
STOP LOSS
$263.01
MAX LOSS
-3%
Volatility-Adjusted Stop Loss
Calculated based on volatility and technical support levels.
Profit Targets (Based on Conservative)
+5% from current
$299.69
+10% from current
$313.96
+15% from current
$328.23
Disclaimer
This comparison involves assets with varying risk profiles. The content is for educational purposes only. The verdict weighs trend, valuation and risk together. Past correlation does not guarantee future lockstep movement. Trading involves risk of loss.

Note: The AI favored LLY based on profitability metrics. This is valid for the specified timeframe only.
08

Questions people ask

Answered from the figures on this page.

Frequently Asked Questions

How do LLY and ABBV compare on valuation?+
LLY trades at a lower P/E ratio (42.01 vs 80.06) and has significantly higher revenue growth (47.7% vs 10.2%), making its valuation more attractive relative to its growth potential.
Which stock offers better profitability?+
LLY offers substantially better profitability with a net profit margin of 33.53% and a return on equity of 102.29%, far exceeding ABBV's figures.
What are the dividend yields for LLY and ABBV?+
ABBV offers a higher dividend yield of 2.42% compared to LLY's yield of 0.53%.
How have LLY and ABBV performed over the past year?+
Over the 12 months to October 18, 2026, LLY's price rose 56.6% and ABBV's rose 24.3%. These are price changes; dividends are not included.
Which is more volatile, LLY or ABBV?+
LLY has been more volatile. Over the 30 days to October 18, 2026, LLY's annualized volatility was 25.6% and ABBV's 18.6%, measured from daily closing prices.
Do LLY and ABBV move together?+
Yes, loosely: over roughly the past year to October 18, 2026, the correlation of their daily returns was +0.37 (+1 means they move in lockstep, 0 means no relationship). Holding both spreads the risk more than owning either alone.

Disclaimer: CleaRank.com is a financial data and analytics provider, not a registered investment advisor, broker-dealer, or financial regulatory body. This AI-generated comparison of LLY vs ABBV is for educational and informational purposes only and does not constitute financial advice, investment recommendations, or an offer to buy or sell any securities or digital assets. The comparison metrics, trade plans, and AI signals are hypothetical, hindsight-based, and simulated. Different asset classes carry different risk profiles - stocks, ETFs, cryptocurrencies, commodities, and forex each have unique regulatory frameworks and risk factors. Market data is provided "as-is" and may be delayed by 15 minutes or more. Past performance does not guarantee future results. You should never invest money you cannot afford to lose. Consult a qualified financial advisor before making any investment decisions. Analysis generated on October 18, 2026.

Disclaimer:

Engaging in financial markets carries significant risk of total capital loss. Markets are volatile, unpredictable, and past success does not guarantee future results. Never invest funds you cannot afford to lose. CleaRank does not offer financial, investment, or advisory services. We provide no recommendations, endorsements, or guarantees regarding market outcomes. You alone are responsible for your decisions.

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